tembetarine

• CAT Number: M074989
• CAS Number: 18446-73-6
• Molecular Formula: C20H26NO4+
• Molecular Weight: 344.43
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: (1S)-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2,2-dimethyl-3,4-dihydro-1H-isoquinolin-2-ium-7-ol
• InChI: InChI=1S/C20H25NO4/c1-21(2)8-7-14-11-20(25-4)18(23)12-15(14)16(21)9-13-5-6-19(24-3)17(22)10-13/h5-6,10-12,16H,7-9H2,1-4H3,(H-,22,23)/p+1/t16-/m0/s1
• InChIKey: ABSDACFLIMOXJY-INIZCTEOSA-O
• SMILES: C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)O)O)OC)C

Tembetarine（Cat No.:M074989） is a pyrrolizidine alkaloid found in plants of the Crotalaria genus, particularly Crotalaria tembetarifo­lia. It possesses toxic properties and is known to cause hepatotoxicity and pulmonary fibrosis in animals. Tembetarine is structurally similar to other pyrrolizidine alkaloids, containing a nine base linked to a nucleic acid moiety. Due to its toxicity, terbutaline and related compounds have garnered attention in pharmacological and toxicological studies. Understanding its mechanisms of action and potential adverse effects is crucial for assessing the safety of herbal remedies containing plants that produce terbutaline and for developing strategies to mitigate its toxic effects.