Tempol-d17,15N

For research use only. Not for therapeutic Use.

  • CAT Number: I041832
  • CAS Number: 90429-66-6
  • Molecular Formula: C9HD1715NO2
  • Molecular Weight: 190.34
  • Purity: ≥95%
Inquiry Now

Tempol-d17,15N is the deuterium labeled Tempol[1]. Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS)[2][3].
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].


Catalog Number I041832
CAS Number 90429-66-6
Molecular Formula C9HD1715NO2
Purity ≥95%
InChI InChI=1S/C9H18NO2/c1-8(2)5-7(11)6-9(3,4)10(8)12/h7,11H,5-6H2,1-4H3/i1D3,2D3,3D3,4D3,5D2,6D2,7D,10+1
InChIKey UZFMOKQJFYMBGY-BIXFOSJQSA-N
SMILES CC1(CC(CC(N1[O])(C)C)O)C
Reference

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
 [Content Brief]

[2]. Vilar-Pereira G, et al. Resveratrol Reverses Functional Chagas Heart Disease in Mice. PLoS Pathog. 2016 Oct 27;12(10):e1005947.
 [Content Brief]

[3]. Chatterjee PK, et al. Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat. Kidney Int. 2000 Aug58(2):658-73.
 [Content Brief]

Request a Quote