Tempol

• CAT Number: I002707
• CAS Number: 2226-96-2
• Molecular Formula: C9H18NO2
• Molecular Weight: 172.24
• Purity: ≥95%
• Synonyms: 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl; 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl; Topical Piperidine Nitroxide MTS-01.
• Target: Metabolic Enzyme/Protease
• Solubility: 10 mM in DMSO
• Storage: 3 years -20 ℃
• InChI: InChI=1S/C9H18NO2/c1-8(2)5-7(11)6-9(3,4)10(8)12/h7,11H,5-6H2,1-4H3
• InChIKey: UZFMOKQJFYMBGY-UHFFFAOYSA-N
• SMILES: [O]N1C(C)(C)CC(O)CC1(C)C

Tempol(CAT: I002707), also known as 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl, is a small molecule antioxidant and radical scavenger. It is a stable nitroxide compound that can readily donate and accept electrons, allowing it to neutralize free radicals and protect cells from oxidative stress. Tempol’s antioxidant properties make it valuable in various research areas, including neuroprotection, cardiovascular health, and cancer therapy. It has shown potential in reducing oxidative damage, inflammation, and tissue injury in several preclinical models. Tempol’s ability to cross the blood-brain barrier has also led to investigations into its neuroprotective effects against conditions such as stroke, traumatic brain injury, and neurodegenerative diseases.