For research use only. Not for therapeutic Use.
Teneligliptin hydrobromide (CAT: I005415) is a potent and long-lasting dipeptidyl peptidase-4 (DPP-4) inhibitor. By competitively inhibiting the DPP-4 enzyme, teneligliptin increases the levels of incretin hormones, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP). This pharmacological action helps regulate blood glucose levels and improves glycemic control in patients with type 2 diabetes mellitus. Teneligliptin is specifically designed to target DPP-4, making it a valuable drug for the management of diabetes.
| Catalog Number | I005415 |
| CAS Number | 906093-29-6 |
| Synonyms | [(2S,4S)-4-[4-(5-methyl-2-phenylpyrazol-3-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone;pentahydrobromide |
| Molecular Formula | C44H65Br5N12O2S2 |
| Purity | ≥95% |
| Target | Dipeptidyl Peptidase |
| Solubility | 10 mM in DMSO |
| Storage | Store at -20°C |
| IC50 | 1 nM |
| IUPAC Name | [(2S,4S)-4-[4-(5-methyl-2-phenylpyrazol-3-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone;pentahydrobromide |
| InChI | InChI=1S/2C22H30N6OS.5BrH/c2*1-17-13-21(28(24-17)18-5-3-2-4-6-18)26-9-7-25(8-10-26)19-14-20(23-15-19)22(29)27-11-12-30-16-27;;;;;/h2*2-6,13,19-20,23H,7-12,14-16H2,1H3;5*1H/t2*19-,20-;;;;;/m00...../s1 |
| InChIKey | LUXIOMHUGCXFIU-MAYGPZJUSA-N |
| SMILES | CC1=NN(C(=C1)N2CCN(CC2)C3CC(NC3)C(=O)N4CCSC4)C5=CC=CC=C5.CC1=NN(C(=C1)N2CCN(CC2)C3CC(NC3)C(=O)N4CCSC4)C5=CC=CC=C5.Br.Br.Br.Br.Br |
| Reference | <p style=”/line-height:25px/”> |
