For research use only. Not for therapeutic Use.
Endonuclease modulator; a nootropic agent and advanced glycation end product (AGE) inhibitor having potential for Alzheimer’s disease (AD) treatment.
Preclinical studies on diabetic rats suggested that tenilsetam may be beneficial in the inhibition of diabetic retinopathy, without amelioration of pericyte loss
| Catalog Number | I037116 |
| CAS Number | 86696-86-8 |
| Molecular Formula | C8H10N2OS |
| Purity | ≥95% |
| IUPAC Name | 3-thiophen-2-ylpiperazin-2-one |
| InChI | InChI=1S/C8H10N2OS/c11-8-7(9-3-4-10-8)6-2-1-5-12-6/h1-2,5,7,9H,3-4H2,(H,10,11) |
| SMILES | C1CNC(=O)C(N1)C2=CC=CS2 |
| Reference | G Munch et al. The cognition-enhancing drug tenilsetam is an inhibitor of protein crosslinking by advance glycosylation. J. Neural. Transm. Sect. 1994, 8(3), 193-208.
TJ Roesler et al. Advanced glycation end product (AGE) inhibition as a possible pharmacotherapeutic strategy in the treatment of Alzheimer’s disease. Drugs Fut. 1999, 24(4), 411. |
