Tenofovir Bis(L-alanine Isopropyl Ester) Amide

• CAT Number: C000334
• CAS Number: 1883563-86-7
• Molecular Formula: C₂₁H₃₆N₇O₆P
• Molecular Weight: 513.53
• Purity: ≥95%
• Synonyms: N,N′-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphinylidene]bis-L-Alanine 1,1′-Bis(1-methylethyl) Ester
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• Appearance: Off-White to Very Dark Yellow Solid
• Storage: -20°C, Inert atmosphere, Light sensitive

Tenofovir Bis(L-alanine Isopropyl Ester) Amide(CAT: C000334) is a novel prodrug of the antiretroviral medication tenofovir. This compound is designed to improve the bioavailability and tissue distribution of tenofovir, making it more effective in treating HIV and hepatitis B infections. Its action method involves conversion to the active form of tenofovir inside the body, where it inhibits the replication of the viral DNA, specifically in the fields of pharmaceutical and organic chemistry.

Reference

Chen, G., et al.: Faming Zhuanli Shenqing, CNВ 105330700 A, 20160217 (2016)