For research use only. Not for therapeutic Use.
Tenuazonic Acid（Cat No.:R034423）is a mycotoxin produced by certain fungi, particularly Alternaria species, which commonly contaminate crops like grains, fruits, and vegetables. This compound has a strong inhibitory effect on protein synthesis, making it toxic to both plants and animals. Due to its cytotoxic properties, tenuazonic acid is studied for potential applications in cancer research, though its toxicity limits direct medical use. In agriculture, it’s a concern for food safety, as exposure to tenuazonic acid through contaminated foods can pose health risks. Its presence is monitored to ensure food quality and safety.
| Catalog Number | R034423 |
| CAS Number | 610-88-8 |
| Synonyms | (5S)-3-Acetyl-1,5-dihydro-4-hydroxy-5-[(1S)-1-methylpropyl]-2H-pyrrol-2-one;?AAC-toxin; L-Tenuazonic acid |
| Molecular Formula | C10H15NO3 |
| Purity | ≥95% |
| Target | Influenza Virus |
| Storage | -20°C |
| IUPAC Name | 4-acetyl-2-butan-2-yl-3-hydroxy-1,2-dihydropyrrol-5-one |
| InChI | InChI=1S/C10H15NO3/c1-4-5(2)8-9(13)7(6(3)12)10(14)11-8/h5,8,13H,4H2,1-3H3,(H,11,14) |
| InChIKey | CEIZFXOZIQNICU-UHFFFAOYSA-N |
| SMILES | CCC(C)C1C(=C(C(=O)N1)C(=O)C)O |
| Reference | Studies in the biochemistry of micro-organisms. 103. Metabolites of Alternaria tenuis Auct.: Culture filtrate products Rosett T. et al. Biochem. J. 1957, 67, 390.<br/><br/>Microbial metabolites with insecticidal properties. Cole M. & Rolinson G. N. Appl. Microbiol. 1972, 24, 660.<br/><br/>Microbial production of tenuazonic acid analogues. Gatenbeck S. & Sierankiewicz J. Antimicrob. Agents Chemother. 1973, 3, 308.<br/><br/>Inhibition of mouse skin tumor promotion by tenuazonic acid. Antony M. et al. Cancer Lett. 1991, 61, 21.</span></p> |
