For research use only. Not for therapeutic Use.
Tepilamide fumarate (XP-23829; PPC-06) is an oral fumaric acid ester, acts as a proagent of Monomethyl fumarate (HY-103252), and is used in the research of moderate to severe chronic plaque psoriasis[1].
| Catalog Number | I010107 |
| CAS Number | 1208229-58-6 |
| Synonyms | 4-O-[2-(diethylamino)-2-oxoethyl] 1-O-methyl (E)-but-2-enedioate |
| Molecular Formula | C11H17NO5 |
| Purity | ≥95% |
| InChI | InChI=1S/C11H17NO5/c1-4-12(5-2)9(13)8-17-11(15)7-6-10(14)16-3/h6-7H,4-5,8H2,1-3H3/b7-6+ |
| InChIKey | AKUGRXRLHCCENI-VOTSOKGWSA-N |
| SMILES | CCN(CC)C(=O)COC(=O)C=CC(=O)OC |
| Reference | [1]. Mrowietz U, et al. Tepilamide Fumarate (PPC-06) Extended Release Tablets in Patients with Moderate-to-Severe Plaque Psoriasis: Safety and Efficacy Results from the Randomized, Double-blind, Placebo-controlled AFFIRM Study. J Clin Aesthet Dermatol. 2022 Jan;15(1):53-58. |
