Terbinafine HCl

• CAT Number: A000945
• CAS Number: 78628-80-5
• Molecular Formula: C21H25N • HCl
• Molecular Weight: 327.90
• Purity: ≥95%
• Synonyms: KWD 2019
• Target: Fungal
• Solubility: >16.3mg/mL in DMSO
• Storage: 3 years -20C powder
• IUPAC Name: (E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine;hydrochloride
• InChI: InChI=1S/C21H25N.ClH/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19;/h5-7,9-14H,16-17H2,1-4H3;1H/b9-5+
• InChIKey: BWMISRWJRUSYEX-SZKNIZGXSA-N
• SMILES: CC(C)(C)C#C/C=C/CN(C)CC1=CC=CC2=CC=CC=C21.Cl

Terbinafine Hydrochloride（Cat No.:A000945）is an antifungal agent commonly used in the treatment of dermatophyte infections such as athlete’s foot, ringworm, and onychomycosis. As a potent inhibitor of squalene epoxidase, an enzyme critical for ergosterol synthesis, Terbinafine HCl disrupts fungal cell membrane integrity, leading to cell death. This broad-spectrum antifungal agent is highly effective against various fungi, including Trichophyton, Epidermophyton, and Microsporum species. Terbinafine Hydrochloride offers a favorable pharmacokinetic profile, with a long half-life, enabling once-daily dosing for systemic infections. It is available in oral and topical formulations for targeted treatment.