For research use only. Not for therapeutic Use.
Terbinafine HCl inhibits ergosterol synthesis by inhibiting squalene epoxidase, used as an antifungal drug.<br>Terbinafine (50 μM to 100 μM) inhibits only marginally the metabolism of ethoxycoumarin (CYP1A2), tolbutamide (CYP2C9), or ethynylestradiol, CsA, and cortisol. Terbinafine proves to be a potent inhibitor of the CYP2D6-mediated dextromethorphan O-demethylation and bufuralol 1-hydroxylation with IC50values of 0.2 μM and 0.25 μM, respectively.
| Catalog Number | A000945 |
| CAS Number | 78628-80-5 |
| Synonyms | KWD 2019 |
| Molecular Formula | C21H25N • HCl |
| Purity | ≥95% |
| Target | Squalene epoxidase |
| Solubility | >16.3mg/mL in DMSO |
| Storage | 3 years -20C powder |
| InChIKey | BWMISRWJRUSYEX-SZKNIZGXSA-N |
