Terconazole-d4

• CAT Number: S000428
• CAS Number: 1398065-50-3
• Molecular Formula: C26H27D4Cl2N5O3
• Molecular Weight: 536.49
• Purity: ≥95%
• IUPAC Name: 2,2,6,6-tetradeuterio-1-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-propan-2-ylpiperazine
• InChI: InChI=1S/C26H31Cl2N5O3/c1-19(2)31-9-11-32(12-10-31)21-4-6-22(7-5-21)34-14-23-15-35-26(36-23,16-33-18-29-17-30-33)24-8-3-20(27)13-25(24)28/h3-8,13,17-19,23H,9-12,14-16H2,1-2H3/t23-,26-/m0/s1/i11D2,12D2
• InChIKey: BLSQLHNBWJLIBQ-WJVDAAAOSA-N
• SMILES: CC(C)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=NC=N4)C5=C(C=C(C=C5)Cl)Cl

Terconazole-d4（Cat No.:S000428） is a deuterated version of terconazole, where four hydrogen atoms are replaced with deuterium. This modification is aimed at enhancing the drug’s metabolic stability and is valuable for detailed pharmacokinetic research. Terconazole is an antifungal medication primarily used to treat yeast infections of the vagina. It works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes, thereby disrupting cell membrane formation and function. The deuterated version, Terconazole-d4, allows researchers to study the drug’s metabolism and degradation pathways more accurately, providing insights into its pharmacological behavior and efficacy.