For research use only. Not for therapeutic Use.
Terfenadine (Cat.No:I003801) was an antihistamine used to treat allergies and hay fever. Due to its potential to cause cardiac arrhythmias, it was withdrawn from the market in many countries and replaced with fexofenadine. Terfenadine’s metabolite, fexofenadine, is now widely used as a safer alternative for allergy relief.
| Catalog Number | I003801 |
| CAS Number | 50679-08-8 |
| Synonyms | MDL 9918;NSC 665802;(±)-Terfenadine;DL-Terfenadine |
| Molecular Formula | C32H41NO2 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | 100 mM in DMSO |
| Storage | -20°C |
| IC50 | 204 nM |
| IUPAC Name | 1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-ol |
| InChI | 1S/C32H41NO2/c1-31(2,3)26-18-16-25(17-19-26)30(34)15-10-22-33-23-20-29(21-24-33)32(35,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-14,16-19,29-30,34-35H,10,15,20-24H2,1-3H3 |
| InChIKey | GUGOEEXESWIERI-UHFFFAOYSA-N |
| SMILES | CC(C)(C)C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O |
