TERT-BUTYL 12-HYDROXY-4 7 10-TRIOXA-

• CAT Number: M133160
• CAS Number: 186020-66-6
• Molecular Formula: C13H26O6
• Molecular Weight: 278.34
• Purity: ≥95%
• Synonyms: Hydroxy-PEG2-(CH2)2-Boc（Cat No.:M133160） is a linker molecule used in the synthesis of antibody-drug conjugates (ADCs) and PROTACs (proteolysis-targeting chimeras). Derived from patent WO2004008101A2 (compound 196), it serves as a connector between the antibody or targeting moiety and the therapeutic payload or protein degrader. This linker provides stability and controlled release of the drug or protein degrader, enhancing the efficacy of ADCs and PROTACs. Hydroxy-PEG2-(CH2)2-Boc plays a crucial role in the design and development of next-generation targeted therapeutics for cancer and other diseases.
• Target: PROTAC
• Storage: RT
• IUPAC Name: tert-butyl 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]propanoate
• InChI: InChI=1S/C13H26O6/c1-13(2,3)19-12(15)4-6-16-8-10-18-11-9-17-7-5-14/h14H,4-11H2,1-3H3
• InChIKey: KSXVEOLRERRELV-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)CCOCCOCCOCCO

Hydroxy-PEG2-(CH2)2-Boc（Cat No.:M133160） is a linker molecule used in the synthesis of antibody-drug conjugates (ADCs) and PROTACs (proteolysis-targeting chimeras). Derived from patent WO2004008101A2 (compound 196), it serves as a connector between the antibody or targeting moiety and the therapeutic payload or protein degrader. This linker provides stability and controlled release of the drug or protein degrader, enhancing the efficacy of ADCs and PROTACs. Hydroxy-PEG2-(CH2)2-Boc plays a crucial role in the design and development of next-generation targeted therapeutics for cancer and other diseases.