tert-Butyl N-[2-[2-(6-chlorohexyloxy)ethoxy]ethyl]carbamate

• CAT Number: C000080
• CAS Number: 920264-35-3
• Molecular Formula: C₁₅H₃₀ClNO₄
• Molecular Weight: 323.86
• Purity: ≥95%
• Synonyms: N-[2-[2-[(6-Chlorohexyl)oxy]ethoxy]ethyl]-carbamic Acid 1,1-Dimethylethyl Ester
• Target: PROTAC Linkers
• Solubility: Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
• Appearance: Colourless Oil
• Storage: 4°C

ert-Butyl N-[2-[2-(6-chlorohexyloxy)ethoxy]ethyl]carbamate(CAT: C000080) is an intermediate compound used in the synthesis of HaloTag O2 Tobramycin. This intermediate plays a crucial role in the stepwise assembly of the final product. HaloTag O2 Tobramycin is a modified form of the antibiotic tobramycin, engineered to incorporate a HaloTag label, enabling its specific binding to HaloTag fusion proteins.

Reference

Koch, K.F., et al.: Antimicrob. Agents Chemother., 309 (1970); Welles, J.S., et al.: Toxicol. Appl. Pharmacol., 22, 332 (1972); Dash, A.K., et al.: Anal. Profiles Drug Subs. Excip., 24, 579 (1996)