Tetracycline

For research use only. Not for therapeutic Use.

  • CAT Number: R065761
  • CAS Number: 60-54-8
  • Molecular Formula: C22H24N2O8
  • Molecular Weight: 444.44
  • Purity: ≥95%
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Tetracycline(Cat No.:R065761) is a broad-spectrum antibiotic widely used in the treatment of various bacterial infections. It belongs to the tetracycline class of antibiotics, which inhibit bacterial protein synthesis by binding to the 30S ribosomal subunit. Tetracycline is effective against a wide range of gram-positive and gram-negative bacteria, making it useful in treating conditions such as respiratory tract infections, urinary tract infections, skin infections, and certain sexually transmitted diseases. Additionally, tetracycline is used in veterinary medicine and has applications in research for studying bacterial resistance mechanisms. Its long history of use and versatility continue to make tetracycline an important tool in both clinical and research settings.


Catalog Number R065761
CAS Number 60-54-8
Synonyms

Tetracyclinum

Molecular Formula C22H24N2O8
Purity ≥95%
Storage -20°C
Overview of Clinical Research

Originator Molecular Research Center<br />
Class Antibacterials; Skin disorder therapies; Tetracyclines<br />
Mechanism of Action Protein 30S ribosomal subunit inhibitors<br />
Orphan Drug Status No<br />
New Molecular Entity No

IUPAC Name (4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
InChI InChI=1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1
InChIKey NWXMGUDVXFXRIG-WESIUVDSSA-N
SMILES C[C@@]1([C@H]2C[C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O
Reference

1. Nihon Rinsho. 2007 Mar 28;65 Suppl 3:675-80.<br />
[Tetracycline].<br />
[Article in Japanese]<br />
Totsuka K(1).<br />
Author information: (1)Department of Infectious Diseases, Tokyo Women&#39;s Medical University.<br />
PMID: 17491443<br />
<br />
2. J Am Pharm Assoc. 1975 Dec;15(12):709-12. doi: 10.1016/s0003-0465(16)33413-9.<br />
Tetracycline.<br />
DOI: 10.1016/s0003-0465(16)33413-9 PMID: 1206202<br />
<br />
3. Crit Rev Oral Biol Med. 1998;9(3):322-32. doi: 10.1177/10454411980090030501.<br />
Tetracycline and its analogues: a therapeutic paradigm in periodontal diseases.<br />
Weinberg MA(1), Bral M.<br />
Author information: (1)Department of Periodontics, New York University College of Dentistry, New York, 10010, USA.<br />
DOI: 10.1177/10454411980090030501 PMID: 9715369

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