Tetraethyl butane-1,4-diylbis(phosphonate)

For research use only. Not for therapeutic Use.

  • CAT Number: I016155
  • CAS Number: 7203-67-0
  • Molecular Formula: C₁₂H₂₈O₆P₂
  • Molecular Weight: 330.29
  • Purity: ≥95%
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Tetraethyl butane-1,4-diylbis(phosphonate) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].<br>PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].


Catalog Number I016155
CAS Number 7203-67-0
Molecular Formula C₁₂H₂₈O₆P₂
Purity ≥95%
Target PROTAC Linkers
Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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