Tetrahydrocoptisine

• CAT Number: I003538
• CAS Number: 4312-32-7
• Molecular Formula: C19H17NO4
• Molecular Weight: 323.34
• Purity: ≥95%
• Solubility: 10 mM in DMSO
• Storage: Room Temperature
• IUPAC Name: 5,7,17,19-tetraoxa-13-azahexacyclo[11.11.0.02,10.04,8.015,23.016,20]tetracosa-2,4(8),9,15(23),16(20),21-hexaene
• InChI: InChI=1S/C19H17NO4/c1-2-16-19(24-10-21-16)14-8-20-4-3-12-6-17-18(23-9-22-17)7-13(12)15(20)5-11(1)14/h1-2,6-7,15H,3-5,8-10H2
• InChIKey: UXYJCYXWJGAKQY-UHFFFAOYSA-N
• SMILES: C1CN2CC3=C(CC2C4=CC5=C(C=C41)OCO5)C=CC6=C3OCO6

Tetrahydro berberine (Cat No.: I003538) has strong anti-inflammatory and anti-endotoxin shock effects, and the anti-inflammatory mechanism may be related to the inhibition of the exudation of inflammatory substances and the secretion of inflammatory cytokines. If you need to, please contact us in time, and we will reply to you as soon as possible within 24 hours.

Reference

[1]. Li W, et al. Anti-inflammatory effect of tetrahydrocoptisine from Corydalis impatiens is a function of possible inhibition of TNF-α, IL-6 and NO production in lipopolysaccharide-stimulated peritoneal macrophages through inhibiting NF-κB activation and MAPK pathway. Eur J Pharmacol. 2013 Sep 5;715(1-3):62-71.

[2]. Li W, et al. Protective effect of tetrahydrocoptisine against ethanol-induced gastric ulcer in mice. Toxicol Appl Pharmacol. 2013 Oct 1;272(1):21-9.