For research use only. Not for therapeutic Use.
Tetramethylrhodamine isothiocyanate (TRITC) is an amine-reactive derivative of rhodamine that is used as a fluorescent label for antibodies and other probes (ex/em max = 552/575 nm). It consists of a base tetramethylrhodamine molecule functionalized with an isothiocyanate reactive group at one of two hydrogen atoms on the bottom ring of the structure. TRITC is reactive towards primary amine groups on proteins, peptides, and other biomolecules.
| Catalog Number | R066590 |
| CAS Number | 95197-95-8 |
| Synonyms | 5(6)-Tetramethylrhodamine isothiocyanate;5(6)-TRITC;TRITC |
| Molecular Formula | C25H21N3O3S |
| Purity | ≥95% |
| Storage | -20°C |
| InChI | InChI=1S/2C25H21N3O3S/c1-27(2)16-6-9-19-22(12-16)31-23-13-17(28(3)4)7-10-20(23)24(19)18-8-5-15(26-14-32)11-21(18)25(29)30;1-27(2)15-8-10-17-21(12-15)31-22-13-16(28(3)4)9-11-18(22)23(17)19-6-5-7-20(26-14-32)24(19)25(29)30/h2*5-13H,1-4H3 |
| InChIKey | DTICYSNQBDFZSM-UHFFFAOYSA-N |
| SMILES | [O-]C(C(C=C(N=C=S)C=C1)=C1C2=C3C=CC(N(C)C)=CC3=[O+]C4=C2C=CC(N(C)C)=C4)=O.[O-]C(C(C(N=C=S)=CC=C5)=C5C6=C7C=CC(N(C)C)=CC7=[O+]C8=C6C=CC(N(C)C)=C8)=O |
| Reference | 1.Li, B.,Oestreich, S. and de Lange, T. Identification of human Rap1: Implications for telomere evolution. Cell 101(5), 471-483 (2000). |
