For research use only. Not for therapeutic Use.
Tetrodotoxin (CAT: I003550) is a potent neurotoxin found in certain marine organisms, such as pufferfish, marine snails, and some species of octopus. It acts by blocking voltage-gated sodium channels, thereby inhibiting the propagation of action potentials in nerve cells. Tetrodotoxin is highly toxic and can cause paralysis and even death if ingested in sufficient quantities. Due to its ability to block nerve impulses, it has been studied for its potential applications in pain management and neurological research.
Catalog Number | I003550 |
CAS Number | 4368-28-9 |
Synonyms | Araregai Toxin;Maculotoxin;Tectin;TTX |
Molecular Formula | C11H17N3O8 |
Purity | ≥95% |
Solubility | 10 mM in DMSO |
Storage | -20°C |
InChIKey | CFMYXEVWODSLAX-QOZOJKKESA-N |
SMILES | NC1=N[C@H](O)[C@@]2([H])[C@]3([H])[C@](CO)(O)[C@]([H])([C@@]4([H])O)O[C@@](O)(O3)[C@@H](O)[C@@]24N1 |
Reference | 1: González-Cano R, Tejada Má, Artacho-Cordón A, Nieto FR, Entrena JM, Wood JN, <br> 3: Hagen NA, Cantin L, Constant J, Haller T, Blaise G, Ong-Lam M, du Souich P, <br> 5: Santamaria CM, Zhan C, McAlvin JB, Zurakowski D, Kohane DS. Tetrodotoxin, |