For research use only. Not for therapeutic Use.
Tetroxoprim is an antimicrobial DHFR inhibitor[1].
Tetroxoprim brings about a 50% in vitro inhibition with E. coli, at a concentration of 4 x 10-9M[1].
| Catalog Number | I037158 |
| CAS Number | 53808-87-0 |
| Synonyms | 5-[[3,5-dimethoxy-4-(2-methoxyethoxy)phenyl]methyl]pyrimidine-2,4-diamine |
| Molecular Formula | C16H22N4O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C16H22N4O4/c1-21-4-5-24-14-12(22-2)7-10(8-13(14)23-3)6-11-9-19-16(18)20-15(11)17/h7-9H,4-6H2,1-3H3,(H4,17,18,19,20) |
| InChIKey | WSWJIZXMAUYHOE-UHFFFAOYSA-N |
| SMILES | COCCOC1=C(C=C(C=C1OC)CC2=CN=C(N=C2N)N)OC |
| Reference | [1]. H S Aschhoff, et al. Tetroxoprim–a new inhibitor of bacterial dihydrofolate reductase. J Antimicrob Chemother. 1979 Nov;5(B):19-25. |
