For research use only, not for therapeutic use.
TFAP (CAT: I019813) is a selective inhibitor of cyclooxygenase-1 (COX-1). COX-1 is an enzyme involved in the production of prostaglandins, which play important roles in inflammation, pain, and other physiological processes. By selectively inhibiting COX-1, TFAP interferes with the synthesis of prostaglandins derived from arachidonic acid, leading to reduced inflammation and pain. This selective inhibition of COX-1 distinguishes TFAP from non-selective COX inhibitors, potentially minimizing unwanted side effects associated with COX-2 inhibition. TFAP’s selective COX-1 inhibitory activity may have therapeutic applications in conditions such as arthritis, cardiovascular diseases, and other inflammatory disorders.
| Catalog Number | I019813 |
| CAS Number | 1011244-68-0 |
| Molecular Formula | C₁₃H₁₀F₃N₃O |
| Purity | ≥95% |
| Reference | [1]. Kakuta H, et al. Identification of urine metabolites of TFAP, a cyclooxygenase-1 inhibitor. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1840-3. |
