For research use only. Not for therapeutic Use.
TG100713(cas# 925705-73-3) is an inhibitor of PI3-kinase (IC50 values are 24, 50, 165 and 215 nM for PI3Kδ, γ, α and β isoforms respectively). Inhibits endothelial cell proliferation.
Catalog Number | R057467 |
CAS Number | 925705-73-3 |
Synonyms | TG 100713;TG-100713;TG100713;3-(2,4-Diamino-6-pteridinyl)phenol; |
Molecular Formula | C12H10N6O |
Purity | ≥95% |
Target | PI3K |
Solubility | Limited solubility |
Storage | <label class= |
IUPAC Name | 3-(2,4-diaminopteridin-6-yl)phenol |
InChI | InChI=1S/C12H10N6O/c13-10-9-11(18-12(14)17-10)15-5-8(16-9)6-2-1-3-7(19)4-6/h1-5,19H,(H4,13,14,15,17,18) |
InChIKey | UOORQSPLBHUQDQ-UHFFFAOYSA-N |
SMILES | C1=CC(=CC(=C1)O)C2=CN=C3C(=N2)C(=NC(=N3)N)N |
Reference | <br /> |