TGFβRI-IN-3

For research use only. Not for therapeutic Use.

  • CAT Number: I047485
  • CAS Number: 2763602-67-9
  • Molecular Formula: C28H23N3O2S
  • Molecular Weight: 465.57
  • Purity: ≥95%
Inquiry Now

TGFβRI-IN-3 represents a highly selective TGFβR1 inhibitor that has potential applications in immuno-oncology, inhibits TGFβR1 at an IC50 of 0.79 nM with 2000-fold selectivity against MAP4K4.


Catalog Number I047485
CAS Number 2763602-67-9
Molecular Formula C28H23N3O2S
Purity ≥95%
Storage 3 years -20°C powder
SMILES CC1=CC=CC(=C1)C2=CC(=CC=N2)NC3=CC=NC4=C3C=CC(=C4)C5=CC=C(C=C5)[S;v6](C)(=O)=O
Reference

[1] Kharbanda A, et al. Eur J Med Chem. 2021 Dec 5;225:113763.

Request a Quote