For research use only. Not for therapeutic Use.
TGFβRI-IN-3 represents a highly selective TGFβR1 inhibitor that has potential applications in immuno-oncology, inhibits TGFβR1 at an IC50 of 0.79 nM with 2000-fold selectivity against MAP4K4.
Catalog Number | I047485 |
CAS Number | 2763602-67-9 |
Molecular Formula | C28H23N3O2S |
Purity | ≥95% |
Storage | 3 years -20°C powder |
SMILES | CC1=CC=CC(=C1)C2=CC(=CC=N2)NC3=CC=NC4=C3C=CC(=C4)C5=CC=C(C=C5)[S;v6](C)(=O)=O |
Reference | [1] Kharbanda A, et al. Eur J Med Chem. 2021 Dec 5;225:113763. |