TH1020

• CAT Number: I014738
• CAS Number: 1841460-82-9
• Molecular Formula: C23H15N7S2
• Molecular Weight: 453.54
• Purity: ≥95%
• Synonyms: TH1020; TH-1020; TH 1020.;4-((4-Benzyl-5-(pyridin4yl)-4H-1,2,4-triazol-3-yl)thio)pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidine
• Target: Anti-infection
• Solubility: Soluble in DMSO
• Storage: 2-8°C
• IUPAC Name: 6-[(4-benzyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene
• InChI: InChI=1S/C23H15N7S2/c1-2-5-15(6-3-1)13-30-20(16-8-11-24-12-9-16)28-29-23(30)32-22-19-18(26-14-27-22)17-7-4-10-25-21(17)31-19/h1-12,14H,13H2
• InChIKey: CBBXTGWSGPEJEE-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)CN2C(=NN=C2SC3=NC=NC4=C3SC5=C4C=CC=N5)C6=CC=NC=C6

TH1020 (Cat No.: I014738) is a selective inhibitor of the protein tyrosine kinase 7 (PTK7), which plays a crucial role in the Wnt signaling pathway. By modulating PTK7, TH1020 has potential therapeutic applications in cancer, where aberrant Wnt signaling contributes to tumor progression and metastasis. This compound is being investigated for its ability to suppress cancer cell growth and enhance the efficacy of other treatments. With its promising mechanism of action, TH1020 offers a novel approach for targeted cancer therapies.