Thalidomide-5-O-C13-NH2 hydrochloride

• CAT Number: I040314
• Molecular Formula: C26H38ClN3O5
• Molecular Weight: 508.05
• Purity: ≥95%
• Synonyms: 5-(13-aminotridecoxy)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride
• InChI: InChI=1S/C26H37N3O5.ClH/c27-16-10-8-6-4-2-1-3-5-7-9-11-17-34-19-12-13-20-21(18-19)26(33)29(25(20)32)22-14-15-23(30)28-24(22)31;/h12-13,18,22H,1-11,14-17,27H2,(H,28,30,31);1H
• InChIKey: OKOWXHFKZIMFFM-UHFFFAOYSA-N
• SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C=C(C=C3)OCCCCCCCCCCCCCN.Cl

Thalidomide-5-O-C13-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-O-C13-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs[1].