Thanatin TFA

• CAT Number: I040097
• Molecular Formula: C103H177N35O27S3.xC2HF3O2
• Molecular Weight: 2433.92 (free base)
• Purity: ≥95%

Thanatin TFA (Cat No.: I040097) is a synthetic antimicrobial peptide derived from the insect species Tachengia. It exhibits potent activity against a broad range of bacterial pathogens by disrupting microbial cell membranes, making it a promising candidate for developing novel antibiotics. Thanatin TFA, which is the trifluoroacetate salt form, enhances the peptide’s stability and solubility for research and potential therapeutic applications. Studies suggest it may be effective against multidrug-resistant bacteria, offering an alternative in the fight against antibiotic-resistant infections.

Reference

[1]. Rachita Dash, et al. Thanatin: An Emerging Host Defense Antimicrobial Peptide with Multiple Modes of Action. Int J Mol Sci. 2021 Feb 3;22(4):1522.
[Content Brief]

[2]. Bo Ma, et al. The antimicrobial peptide thanatin disrupts the bacterial outer membrane and inactivates the NDM-1 metallo-β-lactamase. Nat Commun. 2019 Aug 6;10(1):3517.
[Content Brief]