THAXTOMINE A

• CAT Number: M027542
• CAS Number: 122380-18-1
• Molecular Formula: C22H22N4O6
• Molecular Weight: 438.40
• Purity: ≥95%
• Synonyms: (3R,6S)-3-hydroxy-3-[(3-hydroxyphenyl)methyl]-1,4-dimethyl-6-[(4-nitro-1H-indol-3-yl)methyl]-2,5-piperazinedione
• Target: Bacterial
• Storage: -20°C
• IUPAC Name: (3R,6S)-3-hydroxy-3-[(3-hydroxyphenyl)methyl]-1,4-dimethyl-6-[(4-nitro-1H-indol-3-yl)methyl]piperazine-2,5-dione
• InChI: InChI=1S/C22H22N4O6/c1-24-18(10-14-12-23-16-7-4-8-17(19(14)16)26(31)32)20(28)25(2)22(30,21(24)29)11-13-5-3-6-15(27)9-13/h3-9,12,18,23,27,30H,10-11H2,1-2H3/t18-,22+/m0/s1
• InChIKey: QRDNJYNIEGRRKV-PGRDOPGGSA-N
• SMILES: CN1[C@H](C(=O)N([C@](C1=O)(CC2=CC(=CC=C2)O)O)C)CC3=CNC4=C3C(=CC=C4)[N+](=O)[O-]

Thaxtomine A（Cat No.:M027542）is a naturally occurring alkaloid isolated from Thaxetum species, with notable biological activity. It has demonstrated potent antimicrobial and anticancer properties in preclinical studies, making it a promising candidate for drug development. Thaxtomine A acts by inhibiting cell proliferation and inducing apoptosis in cancer cells, while also exhibiting broad-spectrum antimicrobial effects. Its mechanism of action is thought to involve interference with cellular signaling pathways and the disruption of critical cellular functions. Ongoing research is focused on elucidating its full therapeutic potential and optimizing its pharmacological profile for clinical applications.