For research use only. Not for therapeutic Use.
Thiabendazole(Cat No.:A000403)is a broad-spectrum antifungal and antiparasitic agent commonly used to treat parasitic infections such as strongyloidiasis and trichinosis. It works by inhibiting the enzyme fumarate reductase, which is essential for the energy metabolism of parasites, ultimately leading to their death. Thiabendazole is also used as a post-harvest fungicide in agriculture to protect fruits and vegetables from fungal contamination. In addition to its antiparasitic properties, it has been investigated for antiangiogenic and anticancer activities, making it a versatile compound in both medical and agricultural fields.
CAS Number | 148-79-8 |
Synonyms | 148-79-8; Tiabendazole; Mintezol; Equizole; Mintesol |
Molecular Formula | C₁₀H₇N₃S |
Purity | ≥95% |
Target | Anti-infection |
Storage | -20°C |
IUPAC Name | 4-(1H-benzimidazol-2-yl)-1,3-thiazole |
InChI | InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) |
InChIKey | WJCNZQLZVWNLKY-UHFFFAOYSA-N |
SMILES | C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3 |
Reference | 1: Papadopoulou ES, Genitsaris S, Omirou M, Perruchon C, Stamatopoulou A, 2: Yilmaz E, Ramünke S, Demeler J, Krücken J. Comparison of constitutive and <br> <br> <br> 6: Perruchon C, Pantoleon A, Veroutis D, Gallego-Blanco S, Martin-Laurent F, 7: de Oliveira Neto OF, Arenas AY, Fostier AH. Sorption of thiabendazole in <br> 9: García-Fernández M, Díaz-álvarez M, Martín-Esteban A. Molecularly imprinted <br> |
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