Thiacetarsamide

• CAT Number: I037207
• CAS Number: 531-72-6
• Molecular Formula: C11H12AsNO5S2
• Molecular Weight: 377.26
• Purity: 98%
• Synonyms: Thiacetarsamide free acid; Caparsolate, Arsenamide; Capariside; Thiacetarsamide
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 2-[(4-carbamoylphenyl)-(carboxymethylsulfanyl)arsanyl]sulfanylacetic acid
• InChI: InChI=1S/C11H12AsNO5S2/c13-11(18)7-1-3-8(4-2-7)12(19-5-9(14)15)20-6-10(16)17/h1-4H,5-6H2,(H2,13,18)(H,14,15)(H,16,17)
• InChIKey: YBQWEUNEYYXYOI-UHFFFAOYSA-N
• SMILES: C1=CC(=CC=C1C(=O)N)[As](SCC(=O)O)SCC(=O)O

Thiacetarsamide(CAT: I037207) is an organoarsenic compound known for its antiparasitic properties. It functions by disrupting essential enzymatic processes in parasites through arsenic-mediated inhibition of sulfhydryl group-containing enzymes, ultimately leading to parasite death. Historically, it has been used in veterinary medicine to treat heartworm infections (Dirofilaria immitis) in dogs. Its mechanism of action involves targeting the parasite’s metabolism, making it effective against certain nematodes. While its use in human medicine is limited due to toxicity concerns, Thiacetarsamide Free Acid remains relevant in the Anti-infection research field, particularly for studying arsenic-based antiparasitic agents and their mechanisms.