Thiethylperazine Dimaleate

• CAT Number: R062294
• CAS Number: 1179-69-7
• Molecular Formula: C₂₂H₂₉N₃S₂•2[C₄H₄O₄]
• Molecular Weight: 631.76
• Purity: ≥95%
• Synonyms: 2-(Ethylthio)-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine (Z)-2-Butenedioate (1:2); 2-(Ethylthio)-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine Dimaleate; 2-(Ethylthio)-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine Maleate (1:2)
• Target: Neuronal Signaling
• Storage: -20°C
• IUPAC Name: (Z)-but-2-enedioic acid;2-ethylsulfanyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
• InChI: InChI=1S/C22H29N3S2.2C4H4O4/c1-3-26-18-9-10-22-20(17-18)25(19-7-4-5-8-21(19)27-22)12-6-11-24-15-13-23(2)14-16-24;2*5-3(6)1-2-4(7)8/h4-5,7-10,17H,3,6,11-16H2,1-2H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-
• InChIKey: RVBRTNPNFYFDMZ-SPIKMXEPSA-N
• SMILES: CCSC1=CC2=C(C=C1)SC3=CC=CC=C3N2CCCN4CCN(CC4)C.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O

Thiethylperazine dimaleate（Cat No.:R062294） is a phenothiazine derivative that acts as an orally active antagonist of dopamine D2 and histamine H1 receptors. Additionally, it is a selective activator of ABCC1, which reduces amyloid-β (Aβ) burden in mice. This compound exhibits antiemetic properties, making it effective in managing nausea and vomiting. Moreover, it displays antipsychotic activity and possesses antibacterial properties. The diverse pharmacological properties of Thiethylperazine dimaleate make it a valuable compound for potential therapeutic applications in various conditions, including neuropsychiatric disorders and bacterial infections.