For research use only. Not for therapeutic Use.
Thioguanine-18(CAT: I037229) is a novel and potent inhibitor of the dengue virus serotype 2 NS2B/NS3 protease (DENV2-NS2B/NS3pro), widely used in antiviral and virology research. By specifically targeting the protease critical for viral replication, it disrupts the lifecycle of dengue virus serotype 2, offering a promising avenue for therapeutic development. Its high specificity and activity make Thioguanine-18 an invaluable tool for studying dengue virus biology and exploring antiviral strategies. With exceptional purity and stability, it is ideal for in vitro assays and preclinical research, supporting advancements in combatting dengue and related flaviviral infections.
| Catalog Number | I037229 |
| Synonyms | TG-18; TG 18; TG18; Compound 18 |
| Molecular Formula | C15H21N5O2S |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | S-2-(pentanamido)-9H-purin-6-yl pentanethioate |
| InChI | InChI=1S/C15H21N5O2S/c1-3-5-7-10(21)18-15-19-13-12(16-9-17-13)14(20-15)23-11(22)8-6-4-2/h9H,3-8H2,1-2H3,(H2,16,17,18,19,20,21) |
| InChIKey | HIJYUUHMNCHCQM-UHFFFAOYSA-N |
| SMILES | CCCCC(SC1=C2N=CNC2=NC(NC(CCCC)=O)=N1)=O |
