Thiol-PEG4-Boc

For research use only. Not for therapeutic Use.

  • CAT Number: I016496
  • CAS Number: 564476-33-1
  • Molecular Formula: C₁₅H₃₀O₆S
  • Molecular Weight: 338.46
  • Purity: ≥95%
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Thiol-PEG4-Boc(Cat No.:I016496) is a chemical compound used in bioconjugation and drug delivery applications. It consists of a polyethylene glycol (PEG) chain of four repeating units, terminated with a thiol group and protected with a Boc (tert-butyloxycarbonyl) group. Thiol-PEG4-Boc enables the attachment of PEG to biomolecules through its thiol group, providing improved stability, solubility, and biocompatibility. The Boc protecting group prevents unwanted reactions during conjugation.


CAS Number 564476-33-1
Molecular Formula C₁₅H₃₀O₆S
Purity ≥95%
Target PROTAC Linkers
IUPAC Name tert-butyl 3-[2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethoxy]propanoate
InChI InChI=1S/C15H30O6S/c1-15(2,3)21-14(16)4-5-17-6-7-18-8-9-19-10-11-20-12-13-22/h22H,4-13H2,1-3H3
InChIKey NKLWGDQDZRFINM-UHFFFAOYSA-N
SMILES CC(C)(C)OC(=O)CCOCCOCCOCCOCCS
Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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