Thiol-PEG4-Boc

For research use only. Not for therapeutic Use.

  • CAT Number: I016496
  • CAS Number: 564476-33-1
  • Molecular Formula: C₁₅H₃₀O₆S
  • Molecular Weight: 338.46
  • Purity: ≥95%
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Thiol-PEG4-Boc(Cat No.:I016496) is a chemical compound used in bioconjugation and drug delivery applications. It consists of a polyethylene glycol (PEG) chain of four repeating units, terminated with a thiol group and protected with a Boc (tert-butyloxycarbonyl) group. Thiol-PEG4-Boc enables the attachment of PEG to biomolecules through its thiol group, providing improved stability, solubility, and biocompatibility. The Boc protecting group prevents unwanted reactions during conjugation.


Catalog Number I016496
CAS Number 564476-33-1
Molecular Formula C₁₅H₃₀O₆S
Purity ≥95%
Target PROTAC Linkers
IUPAC Name tert-butyl 3-[2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethoxy]propanoate
InChI InChI=1S/C15H30O6S/c1-15(2,3)21-14(16)4-5-17-6-7-18-8-9-19-10-11-20-12-13-22/h22H,4-13H2,1-3H3
InChIKey NKLWGDQDZRFINM-UHFFFAOYSA-N
SMILES CC(C)(C)OC(=O)CCOCCOCCOCCOCCS
Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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