Thonzylamine hydrochloride

• CAT Number: I037253
• CAS Number: 63-56-9
• Molecular Formula: C16H23ClN4O
• Molecular Weight: 322.84
• Purity: 98%
• Synonyms: Thonzylamine hydrochloride, Anahist, Neohetramine hydrochloride, Novohetramin, Resistab, Thonzylamine HCl
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 2-((2-(Dimethylamino)ethyl)(p-methoxybenzyl)amino)pyrimidine hydrochloride
• InChI: 1S/C16H22N4O.ClH/c1-19(2)11-12-20(16-17-9-4-10-18-16)13-14-5-7-15(21-3)8-6-14;/h4-10H,11-13H2,1-3H3;1H
• InChIKey: HRYJPHOTGFERGT-UHFFFAOYSA-N
• SMILES: N(c1ncccn1)(Cc1ccc(OC)cc1)CCN(C)C.Cl

Thonzylamine hydrochloride (Cat.No:I037253) is an antihistamine and anticholinergic medication. It is commonly used to relieve symptoms of allergies, such as sneezing, itching, and runny nose. Thonzylamine hydrochloride works by blocking the action of histamine and acetylcholine, providing relief from allergic reactions and certain cold symptoms.

Reference

1: Sabry SM, Abdel-Hay MH, Barary MH, Belal TS. Sensitive spectrofluorimetric and spectrophotometric methods for the determination of thonzylamine hydrochloride in pharmaceutical preparations based on coupling with dimethylbarbituric acid in presence of dicyclohexylcarbodiimide. J Pharm Biomed Anal. 2000 Mar;22(2):257-64. PubMed PMID: 10719908.
2: DREYER NB, SLAVIN WJ. Effect of an antihistaminic drug (thonzylamine) on uterine contractility. J Am Med Womens Assoc. 1954 Feb;9(2):35-8. PubMed PMID: 13142908.
3: DUCA CJ, ROTHLAUF MV, SCUDI JV. Further studies on thonzylamine in treatment of experimental tuberculosis. Proc Soc Exp Biol Med. 1951 Aug;77(4):641-3. PubMed PMID: 14891823.