For research use only. Not for therapeutic Use.
THP-PEG6-OH (Cat No.:I017124) is a PROTAClinker belonging to the PEG class. THP-PEG6-OH can be used to synthesize PROTAC molecules. THP-PEG6-OH is also a non-cleavable ADClinker containing 6 units of PEG, which can be used to synthesize antibody drug conjugates (ADC).
Catalog Number | I017124 |
CAS Number | 42607-87-4 |
Molecular Formula | C₁₇H₃₄O₈ |
Purity | ≥95% |
IUPAC Name | 2-[2-[2-[2-[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol |
InChI | InChI=1S/C17H34O8/c18-4-6-19-7-8-20-9-10-21-11-12-22-13-14-23-15-16-25-17-3-1-2-5-24-17/h17-18H,1-16H2 |
InChIKey | ABJWCLPYMPRGRB-UHFFFAOYSA-N |
SMILES | C1CCOC(C1)OCCOCCOCCOCCOCCOCCO |
Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.<br>[2]. Masahiro Tomita, et al. Antibody specifically recognizing resin plasticizer compound. WO2005105846A1. |