Thrombospondin-1 (1016-1023) (human, bovine, mouse)

• CAT Number: M132489
• CAS Number: 149234-04-8
• Molecular Formula: C56H81N13O10S
• Molecular Weight: 1128.39
• Purity: ≥95%
• Synonyms: (2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-phenylpropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanoic acid
• InChI: InChI=1S/C56H81N13O10S/c1-32(2)46(53(76)63-41(24-27-80-5)49(72)67-45(30-36-31-62-40-18-10-9-16-38(36)40)51(74)64-42(55(78)79)19-11-12-25-57)69-54(77)47(33(3)4)68-52(75)44(29-35-20-22-37(70)23-21-35)66-50(73)43(28-34-14-7-6-8-15-34)65-48(71)39(58)17-13-26-61-56(59)60/h6-10,14-16,18,20-23,31-33,39,41-47,62,70H,11-13,17,19,24-30,57-58H2,1-5H3,(H,63,76)(H,64,74)(H,65,71)(H,66,73)(H,67,72)(H,68,75)(H,69,77)(H,78,79)(H4,59,60,61)/t39-,41-,42-,43-,44-,45-,46-,47-/m0/s1
• InChIKey: OBPWCMITEMLEAX-MGQPXDLZSA-N
• SMILES: CC(C)[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CCCCN)C(=O)O)NC(=O)[C@H](CC3=CC=C(C=C3)O)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](CCCN=C(N)N)N

Thrombospondin-1 (Cat No.:M132489) is a multifunctional glycoprotein involved in various cellular processes, including cell adhesion, migration, and angiogenesis. The sequence 1016-1023 refers to a specific peptide region of TSP-1, which is conserved across human, bovine, and mouse species. TSP-1 plays a significant role in regulating extracellular matrix interactions and modulating the activity of growth factors, such as transforming growth factor-beta (TGF-β). It has been implicated in wound healing, immune responses, and tumor progression. Due to its diverse functions, TSP-1 is a target for research in disease therapies, including cancer and vascular disorders.