For research use only. Not for therapeutic Use.
Thromboxane B2(Cat.No: R054217) is a stable, biologically inert metabolite formed from the non-enzymatic hydrolysis of TXA<sub>2</sub>, which has a half-<wbr></wbr>life of about 30 seconds. Urinary analysis of TXB<sub>2</sub> accurately reflects intrarenal TXA<sub>2</sub> synthesis, while measurement of 11-<wbr></wbr>dehydro and 2,3-<wbr></wbr>dinor TX metabolites gives the best estimate of systemic TXA<sub>2</sub> secretion.
| Catalog Number | R054217 |
| CAS Number | 54397-85-2 |
| Synonyms | 8-(1-Hydroxy-3-oxopropyl)-9,12-dihydroxy-5,10-heptadecadienoic Acid Hemiacetal; (5Z,9α,13E,15S)9,11,15-Trihydroxythromboxa-5,13-dien-1-oic Acid; TXB2; (5Z)-7-[(2R,3S,4S)-Tetrahydro-4,6-dihydroxy-2-[(1E,3S)-3-hydroxy-1-octenyl]-2H-pyran-3-yl]-5-hepten |
| Molecular Formula | C20H34O6 |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | (Z)-7-[(2R,3S,4S)-4,6-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]oxan-3-yl]hept-5-enoic acid |
| InChI | InChI=1S/C20H34O6/c1-2-3-6-9-15(21)12-13-18-16(17(22)14-20(25)26-18)10-7-4-5-8-11-19(23)24/h4,7,12-13,15-18,20-22,25H,2-3,5-6,8-11,14H2,1H3,(H,23,24)/b7-4-,13-12+/t15-,16-,17-,18+,20?/m0/s1 |
| InChIKey | XNRNNGPBEPRNAR-JQBLCGNGSA-N |
| SMILES | CCCCCC(C=CC1C(C(CC(O1)O)O)CC=CCCCC(=O)O)O |
