Thymotrinan

For research use only. Not for therapeutic Use.

  • CAT Number: I037279
  • CAS Number: 85465-82-3
  • Molecular Formula: C16H31N7O6
  • Molecular Weight: 417.46
  • Purity: 98%
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Thymotrinan (Cat.No:I037279) is a thymopoietin oligopeptide. Inquire Thymotrinan online by filling out the inquiry form, we will get back to you within 24 hours!


Catalog Number I037279
CAS Number 85465-82-3
Synonyms

Thymotrinan; RGH 0205; RGH-0205; RG 0205; Thymotrinanum;

Molecular Formula C16H31N7O6
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name L-arginyl-L-lysyl-L-aspartic acid
InChI InChI=1S/C16H31N7O6/c17-6-2-1-5-10(14(27)23-11(15(28)29)8-12(24)25)22-13(26)9(18)4-3-7-21-16(19)20/h9-11H,1-8,17-18H2,(H,22,26)(H,23,27)(H,24,25)(H,28,29)(H4,19,20,21)/t9-,10-,11-/m0/s1
InChIKey MJINRRBEMOLJAK-DCAQKATOSA-N
SMILES O=C(O)C[C@@H](C(O)=O)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)N)=O)=O
Reference

1: Zhang Y, Feng J, Cui L, Zhang Y, Li W, Li C, Shi N, Chen Y, Kong W. Investigation Into Efficiency of a Novel Glycol Chitosan-Bestatin Conjugate to Protect Thymopoietin Oligopeptides From Enzymatic Degradation. J Pharm Sci. 2016 Feb;105(2):828-837. doi: 10.1002/jps.24567. Epub 2016 Jan 11. PubMed PMID: 26173563.
2: Schmidt MC, Rubas W, Merkle HP. Nasal epithelial permeation of thymotrinan (TP3) versus thymocartin (TP4): competitive metabolism and self-enhancement. Pharm Res. 2000 Feb;17(2):222-8. PubMed PMID: 10751039.
3: Heizmann J, Langguth P, Biber A, Oschmann R, Merkle HP, Wolffram S. Enzymatic cleavage of thymopoietin oligopeptides by pancreatic and intestinal brush-border enzymes. Peptides. 1996;17(7):1083-9. PubMed PMID: 8959740.
4: Görög S, Balogh G, Csehi A, Csizér E, Gazdag M, Halmos Z, Hegedüs B, Herényi B, Horváth P, Laukó A. Estimation of impurity profiles in drugs and related materials. Part 11–The role of chromatographic and spectroscopic methods in the estimation of side-reactions in drug syntheses. J Pharm Biomed Anal. 1993 Nov-Dec;11(11-12):1219-26. Review. PubMed PMID: 8123737.
5: Baló-Banga JM, Pintér E, Németh G. [Incidence of SLE in a patient thymectomized for myasthenia gravis]. Orv Hetil. 1993 Jun 20;134(25):1369-72. Hungarian. PubMed PMID: 8332357.

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