Thyroglobulin

• CAT Number: I040641
• CAS Number: 9010-34-8
• Purity: ≥95%

Thyroglobulin(CAT: I040641) is a large, 660 kDa dimeric glycoprotein synthesized by follicular cells of the thyroid gland, functioning exclusively within the thyroid follicular lumen. It serves as a critical precursor and storage protein for the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin contains multiple tyrosine residues that undergo iodination, forming hormonogenic sites essential for T3/T4 biosynthesis. Additionally, it plays a central role in iodine storage and hormone regulation, making it indispensable in thyroid physiology and endocrinology research. Thyroglobulin is widely used in studies of thyroid hormone metabolism, autoimmune thyroid disease, and hormone assay development.