For research use only. Not for therapeutic Use.
Tiafenacil is a new protoporphyrinogen IX oxidase (PPO)-inhibiting herbicide, with IC50 values of 22 to 28 nM for various plant species, including amaranth (Amaranthus tuberculatus), soybean (Glycine max), arabidopsis (Arabidopsis thaliana), and rapeseed (Brassica napus)[1].
Tiafenacil has low oral and dermal acute toxicity[1].
In velvetleaf, Tiafenacil causes severe growth inhibition at 1 µM and results in desiccation and death at 5 µM[1].
| Catalog Number | I044660 |
| CAS Number | 1220411-29-9 |
| Synonyms | methyl 3-[2-[2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]phenyl]sulfanylpropanoylamino]propanoate |
| Molecular Formula | C19H18ClF4N3O5S |
| Purity | ≥95% |
| InChI | InChI=1S/C19H18ClF4N3O5S/c1-9(17(30)25-5-4-16(29)32-3)33-13-7-12(11(21)6-10(13)20)27-15(28)8-14(19(22,23)24)26(2)18(27)31/h6-9H,4-5H2,1-3H3,(H,25,30) |
| InChIKey | QPTPZPIXUPELRM-UHFFFAOYSA-N |
| SMILES | CC(C(=O)NCCC(=O)OC)SC1=C(C=C(C(=C1)N2C(=O)C=C(N(C2=O)C)C(F)(F)F)F)Cl |
| Reference | [1]. Joonghyuk Park, et al. Biochemical and physiological mode of action of tiafenacil, a new protoporphyrinogen IX oxidase-inhibiting herbicide. Pestic Biochem Physiol. 2018 Nov;152:38-44. |
