Tianeptine-d12 Methyl Ester

• CAT Number: R011651
• CAS Number: 1216805-56-9
• Molecular Formula: C22H27ClN2O4S
• Molecular Weight: 463.051
• Purity: ≥95%
• Synonyms: 7-[(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)amino]-Heptanoic Acid-d12 Methyl Ester; Coaxil-d12 Methyl Ester
• Storage: Store at -20°C
• IUPAC Name: methyl 7-[(3-chloro-6-methyl-5,5-dioxo-11H-benzo[c][2,1]benzothiazepin-11-yl)amino]-2,2,3,3,4,4,5,5,6,6,7,7-dodecadeuterioheptanoate
• InChI: InChI=1S/C22H27ClN2O4S/c1-25-19-10-7-6-9-17(19)22(24-14-8-4-3-5-11-21(26)29-2)18-13-12-16(23)15-20(18)30(25,27)28/h6-7,9-10,12-13,15,22,24H,3-5,8,11,14H2,1-2H3/i3D2,4D2,5D2,8D2,11D2,14D2
• InChIKey: AOVSYZQNKXYQOR-SZXIOYOXSA-N
• SMILES: [2H]C([2H])(C(=O)OC)C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])NC1C2=C(C=C(C=C2)Cl)S(=O)(=O)N(C3=CC=CC=C13)C

Tianeptine-d12 Methyl Ester is a deuterated form of tianeptine, an atypical antidepressant known for its action on the glutamatergic system and modulation of neuroplasticity. This compound features twelve deuterium atoms, which enhance its stability and allow for precise tracking in pharmacokinetic studies, drug metabolism research, and isotope-dilution mass spectrometry. The methyl ester form makes it particularly useful in studies focused on drug delivery and bioavailability. Tianeptine-d12 Methyl Ester is essential for investigating the absorption, distribution, metabolism, and excretion (ADME) of tianeptine, particularly in understanding its pharmacokinetic profile and metabolic pathways. It serves as a reliable internal standard in analytical chemistry, ensuring accurate and reproducible results in the study of antidepressants and neuropharmacological research.