For research use only. Not for therapeutic Use.
Tilbroquinol（Cat No.:I000059）is an antiprotozoal agent commonly used to treat amoebic dysentery and other intestinal infections caused by Entamoeba histolytica. It acts by targeting the protozoan’s metabolic processes, disrupting its ability to thrive in the intestinal lumen. Tilbroquinol is effective as a luminal amoebicide, focusing on eliminating the parasite within the gut while minimizing systemic absorption, which reduces potential side effects. Its high efficacy and safety profile make it a valuable treatment option for amoebiasis, particularly in asymptomatic carriers, helping to prevent disease transmission and recurrence.
| Catalog Number | I000059 |
| CAS Number | 7175-09-9 |
| Synonyms | 7-bromo-5-methylquinolin-8-ol |
| Molecular Formula | C10H8BrNO |
| Purity | ≥95% |
| Target | Parasite |
| Solubility | 10 mM in DMSO |
| Storage | Store at -20C |
| IUPAC Name | 7-bromo-5-methylquinolin-8-ol |
| InChI | InChI=1S/C10H8BrNO/c1-6-5-8(11)10(13)9-7(6)3-2-4-12-9/h2-5,13H,1H3 |
| InChIKey | JMOVFFLYGIQXMM-UHFFFAOYSA-N |
| SMILES | CC1=CC(=C(C2=C1C=CC=N2)O)Br |
| Reference | </br>1:[Acute hepatitis caused by the combination of tiliquinol and tilbroquinol (Intétrix)]. Caroli-Bosc FX, Chichmanian RM, Caumes E, Saint-Paul MC, Marty P, Demarquay JF, Hastier P, Delmont JP.Gastroenterol Clin Biol. 1996;20(6-7):605-6. French. No abstract available. PMID: 8881577 </br>2:[In vitro sensitivity of Vibrio cholerae serotype 0:139 to an intestinal antiseptic tiliquinol-tilbroquinol combination]. Bougoudogo F, Fournier JM, Dodin A.Bull Soc Pathol Exot. 1994;87(1):38-40. French. PMID: 8003903 </br>3:[Neuropathy and ocular involvement following prolonged use of tilbroquinol and tiliquinol]. Basdevant A, Soffer M, Saragoussi JJ, Raison J, Pouillon M, Guy-Grand B.Rev Med Interne. 1985 Jan;6(1):65-7. French. No abstract available. PMID: 3923584 |
