Tiotropium-d3 bromide

• CAT Number: S000306
• CAS Number: 1127226-56-5
• Molecular Formula: C19H19D3BrNO4S2
• Molecular Weight: 475.43
• Purity: ≥95%
• IUPAC Name: [9-methyl-9-(trideuteriomethyl)-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonan-7-yl] 2-hydroxy-2,2-dithiophen-2-ylacetate;bromide
• InChI: InChI=1S/C19H22NO4S2.BrH/c1-20(2)12-9-11(10-13(20)17-16(12)24-17)23-18(21)19(22,14-5-3-7-25-14)15-6-4-8-26-15;/h3-8,11-13,16-17,22H,9-10H2,1-2H3;1H/q+1;/p-1/i1D3
• InChIKey: DQHNAVOVODVIMG-NIIDSAIPSA-M
• SMILES: C[N+]1(C2CC(CC1C3C2O3)OC(=O)C(C4=CC=CS4)(C5=CC=CS5)O)C.[Br-]

Tiotropium-d3 bromide（Cat No.:S000306） is a deuterated form of tiotropium bromide, where three hydrogen atoms are replaced with deuterium. Tiotropium is a long-acting muscarinic antagonist (LAMA) widely used as a bronchodilator to manage chronic obstructive pulmonary disease (COPD). The addition of deuterium increases the stability of the molecule, facilitating more accurate pharmacokinetic and metabolic studies. This detailed analysis helps in understanding how tiotropium is absorbed, distributed, metabolized, and excreted in the body, leading to more effective treatment strategies, optimized dosing, and potentially enhanced safety for patients with respiratory conditions.