Tis108

• CAT Number: H000076
• CAS Number: 1315459-30-3
• PubChem Substance ID: 102359173
• Molecular Formula: C20H21N3O2
• Molecular Weight: 335.40
• Purity: 98%
• Synonyms: 6-phenoxy-1-phenyl-2-(1H-1,2,4-triazol-1-yl)hexan-1-one
• Appearance: White solid
• Storage: Store at 0-8 °C
• Analysis method: HPLC
• IUPAC Name: 6-phenoxy-1-phenyl-2-(1,2,4-triazol-1-yl)hexan-1-one
• InChI: InChI=1S/C20H21N3O2/c24-20(17-9-3-1-4-10-17)19(23-16-21-15-22-23)13-7-8-14-25-18-11-5-2-6-12-18/h1-6,9-12,15-16,19H,7-8,13-14H2
• InChIKey: PCSREBFOVZSWQV-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)C(=O)C(CCCCOC2=CC=CC=C2)N3C=NC=N3

TIS108（Cat No.:H000076）is a novel antifungal agent targeting ergosterol biosynthesis, crucial for fungal cell membrane integrity. It effectively inhibits key enzymes in the pathway, disrupting fungal growth and proliferation. TIS108 is particularly potent against various pathogenic fungi, including strains resistant to conventional antifungals. Its unique mechanism of action and broad-spectrum activity make it a promising candidate for treating invasive fungal infections. TIS108’s potential to address antifungal resistance highlights its importance in pharmaceutical research, aiming to enhance therapeutic options for difficult-to-treat fungal diseases.