Tixocortol 21-Pivalate

• CAT Number: R050926
• CAS Number: 55560-96-8
• Molecular Formula: C26H38O5S
• Molecular Weight: 462.645
• Purity: ≥95%
• Synonyms: (11β)-21-[(2,2-Dimethyl-1-oxopropyl)thio]-11,17-dihydroxypregn-4-ene-3,20-dione; JO 1016; Pivalone; Rectovalone; Tiovalon; Tixocortol Pivalate
• Storage: -20°C
• IUPAC Name: S-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanethioate
• InChI: InChI=1S/C26H38O5S/c1-23(2,3)22(30)32-14-20(29)26(31)11-9-18-17-7-6-15-12-16(27)8-10-24(15,4)21(17)19(28)13-25(18,26)5/h12,17-19,21,28,31H,6-11,13-14H2,1-5H3/t17-,18-,19-,21+,24-,25-,26-/m0/s1
• InChIKey: BISFDZNIUZIKJD-XDANTLIUSA-N
• SMILES: CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CSC(=O)C(C)(C)C)O)C)O

Tixocortol 21-pivalate is a synthetic corticosteroid derivative used in dermatological preparations for its anti-inflammatory and immunosuppressive properties. It is an esterified form of tixocortol, enhancing its stability and skin penetration. Tixocortol 21-pivalate is employed in topical creams and ointments to treat skin conditions such as eczema, psoriasis, and dermatitis. Research on this compound focuses on optimizing formulations and assessing its therapeutic efficacy and safety profiles for various dermatological applications.