For research use only. Not for therapeutic Use.
TJ191 (Cat.No:I037336) is a selective anti-cancer agent, targeting low TβRIII-expressing malignant T-cell leukemia/lymphoma cells.
| Catalog Number | I037336 |
| CAS Number | 1522415-97-9 |
| Synonyms | TJ191; TJ-191; TJ 191 |
| Molecular Formula | C13H21NO2S |
| Purity | 98% |
| Target | Apoptosis |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 2-Amino-3-methylcarboxy-5-heptyl-thiophene |
| InChI | InChI=1S/C13H21NO2S/c1-3-4-5-6-7-8-10-9-11(12(14)17-10)13(15)16-2/h9H,3-8,14H2,1-2H3 |
| InChIKey | HUFNXSPJUAHQHP-UHFFFAOYSA-N |
| SMILES | CCCCCCCC1=CC(C(OC)=O)=C(N)S1 |
| Reference | 1: El-Gazzar A, Noppen S, Thomas J, Dehaen W, Balzarini J, Liekens S. 2-Amino-3-methylcarboxy-5-heptyl-thiophene (TJ191) is a selective anti-cancer small molecule that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells. Oncotarget. 2017 Dec 15;9(5):6259-6269. doi: 10.18632/oncotarget.23501. eCollection 2018 Jan 19. PubMed PMID: 29464070; PubMed Central PMCID: PMC5814210. |
