For research use only. Not for therapeutic Use.
TLR7 agonist 3 (Compound 2) is a potent agonist of toll-like receptor 7 (TLR7). TLR7 has an important role in immune activation processes and represents an emerging agent discovery target for the development of immunomodulators[1].
| Catalog Number | I037350 |
| CAS Number | 1229024-78-5 |
| Synonyms | 1-(4-amino-2-butylimidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol |
| Molecular Formula | C18H24N4O |
| Purity | ≥95% |
| InChI | InChI=1S/C18H24N4O/c1-4-5-10-14-21-15-16(22(14)11-18(2,3)23)12-8-6-7-9-13(12)20-17(15)19/h6-9,23H,4-5,10-11H2,1-3H3,(H2,19,20) |
| InChIKey | GITVQUOQRHRGQQ-UHFFFAOYSA-N |
| SMILES | CCCCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N |
| Reference | [1]. Urban Švajger, et al. New antagonists of toll-like receptor 7 discovered through 3D ligand-based virtual screening. Medicinal Chemistry Research. 2015. 24: 362-371. |
