For research use only. Not for therapeutic Use.
TLR7 agonist 6 (compound IIb-19) is an TLR7 agonist with an EC50 value of 1.0 nM[1].
| Catalog Number | I041711 |
| CAS Number | 2380231-86-5 |
| Synonyms | 16-amino-6-[4-[(cyclobutylamino)methyl]phenyl]-8,13-dioxa-1,15,18,21-tetrazatetracyclo[12.5.2.13,7.017,20]docosa-3(22),4,6,14,16,20-hexaen-19-one |
| Molecular Formula | C27H30N6O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C27H30N6O3/c28-24-23-25-32-26(31-24)36-13-2-1-12-35-22-14-18(16-33(25)27(34)30-23)8-11-21(22)19-9-6-17(7-10-19)15-29-20-4-3-5-20/h6-11,14,20,29H,1-5,12-13,15-16H2,(H,30,34)(H2,28,31,32) |
| InChIKey | ZECLFMPOPJHUCX-UHFFFAOYSA-N |
| SMILES | C1CCOC2=NC(=C3C(=N2)N(CC4=CC(=C(C=C4)C5=CC=C(C=C5)CNC6CCC6)OC1)C(=O)N3)N |
| Reference | [1]. Purandare AV, et al. Preparation of macrocyclic purine compounds as toll-like receptor 7 (TLR7) agonists: World Intellectual Property Organization, WO2019209811 A1. 2019-10-31. |
