For research use only. Not for therapeutic Use.
TLX agonist 1 (ccrp2) is an orphan nuclear receptor tailless (TLX, NR2E1) modulator (EC50=1μM; Kd= 650 nM). TLX agonist 1 potentiates TLX transcriptional repressive activity[1].
| Catalog Number | I017309 |
| CAS Number | 958323-31-4 |
| Synonyms | (4-benzhydrylpiperazin-1-yl)-(1,5-dimethylpyrazol-3-yl)methanone |
| Molecular Formula | C23H26N4O |
| Purity | ≥95% |
| InChI | InChI=1S/C23H26N4O/c1-18-17-21(24-25(18)2)23(28)27-15-13-26(14-16-27)22(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-12,17,22H,13-16H2,1-2H3 |
| InChIKey | SSGJAUSSGPIZEE-UHFFFAOYSA-N |
| SMILES | CC1=CC(=NN1C)C(=O)N2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4 |
| Reference | [1]. Benod C, et al. The human orphan nuclear receptor tailless (TLX, NR2E1) is druggable. PLoS One. 2014 Jun 17;9(6):e99440. |
