TM-P4-Thal

• CAT Number: I037363
• Molecular Formula: C50H74N6O10S
• Molecular Weight: 951.23
• Purity: 98%
• Synonyms: TM-P4-Thal; TMP4-Thal; TM P4-Thal; TM-P4Thal; TM-P4 Thal; TMP4Thal; TM P4 Thal
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-N-((S)-1-oxo-1-(phenylamino)-6-tetradecanethioamidohexan-2-yl)-3,6,9,12-tetraoxapentadecan-15-amide
• InChI: InChI=1S/C50H74N6O10S/c1-2-3-4-5-6-7-8-9-10-11-15-24-45(67)52-28-17-16-22-41(47(59)53-38-19-13-12-14-20-38)54-44(58)27-30-63-32-34-65-36-37-66-35-33-64-31-29-51-40-23-18-21-39-46(40)50(62)56(49(39)61)42-25-26-43(57)55-48(42)60/h12-14,18-21,23,41-42,51H,2-11,15-17,22,24-37H2,1H3,(H,52,67)(H,53,59)(H,54,58)(H,55,57,60)/t41-,42?/m0/s1
• InChIKey: CYVGGMWMJPYYNF-DYJLHVNUSA-N
• SMILES: O=C(N[C@@H](CCCCNC(CCCCCCCCCCCCC)=S)C(NC1=CC=CC=C1)=O)CCOCCOCCOCCOCCNC2=CC=CC(C(N3C(CC4)C(NC4=O)=O)=O)=C2C3=O

TM-P4-Thal（Cat No.:I037363）is a compound that combines thalidomide with a novel peptide-based moiety (TM-P4), designed to enhance its therapeutic potential. Thalidomide is known for its anti-inflammatory, immunomodulatory, and antiangiogenic properties, primarily used in conditions like multiple myeloma and leprosy. TM-P4-Thal is being studied for its potential to improve thalidomide’s targeting ability, increasing its effectiveness in treating diseases such as cancer, inflammatory disorders, and autoimmune diseases. The peptide component aims to improve the selectivity and efficacy of thalidomide while potentially reducing its side effects. Ongoing research is exploring its clinical applications.