TN-16

• CAT Number: R066940
• CAS Number: 33016-12-5
• Molecular Formula: C19H18N2O2
• Molecular Weight: 306.36
• Purity: ≥95%
• Synonyms: 2-benzyl-3-hydroxy-4-(C-methyl-N-phenylcarbonimidoyl)-1,2-dihydropyrrol-5-one
• InChI: InChI=1S/C19H18N2O2/c1-13(20-15-10-6-3-7-11-15)17-18(22)16(21-19(17)23)12-14-8-4-2-5-9-14/h2-11,16,22H,12H2,1H3,(H,21,23)
• InChIKey: IHXKJZIDPGITHW-UHFFFAOYSA-N
• SMILES: CC(=NC1=CC=CC=C1)C2=C(C(NC2=O)CC3=CC=CC=C3)O

TN-16 is a potent inhibitor of microtubule polymerization with IC50 of 0.4-1.7 µM[1].

Reference

[1]. Arai T. Inhibition of microtubule assembly in vitro by TN-16, a synthetic antitumor drug. FEBS Lett. 1983 May 8;155(2):273-6. 
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