For research use only. Not for therapeutic Use.
TNIK-IN-7 (Compound 8) is an inhibitor of Traf2 and Nck-interacting kinase (TNIK), with IC50 of 11 nM, that has antitumor activity[1].
| Catalog Number | I040537 |
| CAS Number | 1417795-24-4 |
| Synonyms | 4-methoxy-3-[2-(4-morpholin-4-ylanilino)pyridin-4-yl]benzonitrile |
| Molecular Formula | C23H22N4O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C23H22N4O2/c1-28-22-7-2-17(16-24)14-21(22)18-8-9-25-23(15-18)26-19-3-5-20(6-4-19)27-10-12-29-13-11-27/h2-9,14-15H,10-13H2,1H3,(H,25,26) |
| InChIKey | FOWKPAQNTXMWQQ-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C(C=C1)C#N)C2=CC(=NC=C2)NC3=CC=C(C=C3)N4CCOCC4 |
| Reference | [1]. Koc-Kan Ho, et al. Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. Bioorg Med Chem Lett. 2013 Jan 15;23(2):569-73. |
